Research Assistant
Research Division
Your role is to conduct experiments assigned by the Senior Scientist. You must possess the relevant scientific knowledge required, strong communication skills to work with your team, and a pro-active mindset for continuous improvement.
Job Description
- Tool generation – expression vector construction, expression, stable cell lines development
- Antibody generation – B cell cloning, antibody library
- Antibody screening – ELISA, FACS, cell-based functional assay etc.
- Lead optimization – expression vector construction, expression
- Protein Analysis – Biacore analysis, column chromatography analysis (IE, SE, RP etc.), SDS-PAGE, other physiochemical analysis
- Pharmacokinetics – sample measurement in in vitro and in vivo samples and PK simulation
- Protein purification – column chromatography, SDS-PAGE, Western Blotting
- Pharmacology (Oncology) – Development and performance of functional cell-based and cell-free assay, preferably in immunology and/or oncology
Requirements
- Degree in Biomedical Science/Biotechnology/Molecular Biotechnology or a related field with at least 1-2 years of related working experience.
- Familiar with basic laboratory procedures. Experience in Molecular Biology, Protein Chemistry, Protein Purification techniques, Cell culture, Flow Cytometry, Confocal Microscopy and other relevant skills will be an added advantage.
- Fresh graduates are welcome to apply
Job Description:
- Tool generation – expression vector construction and molecular cloning, protein expression, stable cell lines development
- Drug screening – ELISA, FACS, cell-based functional assay, confocal microscopy, SDS-PAGE, Western Blotting, qPCR
- Cell culture – Suspension cell culture and adherent cell culture, 3D cell culture models, such as spheroid, organoid, organ slice and organ-on-a-chip
- Lab management
Requirements:
- Degree in Biomedical Science/Biotechnology/Molecular Biotechnology or a related field with at least 1-2 years of related working experience.
- Familiar with basic laboratory procedures especially mammalian cell culture.
- Experience in Molecular Biology, Protein Chemistry, 3D Cell culture, Cell engineering, Flow Cytometry, Confocal Microscopy, NGS analysis and other relevant skills will be an added advantage.
- In vivo sample handling experience is plus but not necessary.
- Programming skill ,for example Python, is also plus.
- Working experience in either industry or academia is welcome.
Overview
We are seeking a motivated Research Assistant to join our Pharmacokinetics Unit. In this role, you will support Pharmacokinetics studies for drug candidates by performing laboratory experiments, analyzing data and contributing to scientific discussions.
You will work according to established SOPs, ensure high standards of data quality and integrity, and participate in routine laboratory maintenance. You will also collaborate closely with team members and colleagues from other units.
You communicate clearly, collaborate well in multidisciplinary settings, and take ownership of assigned tasks. You are eager to learn, open to feedback, and committed to continuously improving your technical skills. You work with care and attention to detail, stay organized, and manage multiple tasks in a fast-paced environment.
Key responsibilities:
- Support bioanalytical measurement of plasma and tissue samples.
- Conduct quantitative immunoassays and related analytical methods, including ELISA, ECL-based assays, Western blotting, immunoprecipitation, and other relevant assay formats.
- Perform or support flow cytometry, cell-based assays, confocal microscopy, qPCR, and other laboratory techniques required for assigned studies.
- Generate high-quality experimental data and conduct basic data processing, analysis, and visualization using tools such as Excel, GraphPad Prism, Spotfire, R, or equivalent software.
- Follow experimental protocols carefully and ensure all procedures are performed consistently, safely, and in compliance with SOPs.
Requirements:
- Degree in Biomedical Science/Biochemistry/Chemical Biology/Biotechnology/Molecular Biotechnology or related field.
- 0-2 years of relevant lab experience in a related field. Fresh graduates are welcome to apply.
- Familiarity with basic laboratory procedures, including sample preparation, pipetting, reagent preparation, and data recording.
- Hands-on experience with one or more of the following techniques is preferred:
- Plasma or tissue sample analysis
- Quantitative immunoassays, such as ELISA or ECL-based assays
- Western blotting or immunoprecipitation
- Flow cytometry
- Cell-based assays
- Confocal microscopy
- qPCR
- Basic data analysis skills using Excel or equivalent software.
- Experience with lab automation and coding in VBA, R, or Python would be an advantage.